Inventor Flint Lockwood thought he saved the world when he destroyed his most infamous invention -- a machine that turned water into food causing cheeseburger rain and spaghetti tornadoes. But Flint soon learns that his invention survived and is now combining food and animals to create – "foodimals!" Flint and his friends embark on an adventurously mouth-watering mission to battle hungry tacodiles, shrimpanzees, hippotatomuses, cheesepiders and other foodimals to save the world – again!